The third edition of this best-selling volume provides an overview of
current knowledge of the wide variety of mechanisms used by bacterial
pathogens in establishing infection, producing disease, and
persisting in the host. Internationally recognized authorities in the
field review bacterial invasion, colonization, and survival;
bacterial evasion of host defense mechanisms; bacterial effects on
host cell function; and identification, regulation, and transfer of
virulence genes. The final chapter presents an interesting
examination of new methods for studying virulence mechanisms in the
complex in vivo environment, a major development in studies of
bacterial pathogenicity. The overall emphasis is on understanding the
mechanisms of host-pathogen interactions rather than on focusing on
specific research approaches.
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