A genetic switch
A genetic switch: phage lambda revisited Mark Ptashne,
Publisher: Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory Press, c2004.
ISBN: 0879697164
DDC: 579.26
LCC: QR342
Edition: (pbk. : alk. paper)
Summary:
"The first edition of A Genetic Switch has become a classic
exposition of gene regulation, explaining in simple molecular terms
how proteins bind DNA and turn genes on and off as the virus lambda
grows in bacteria. To that original text, reprinted here with small
modifications, the author has added a chapter describing recent
advances that extend and deepen our understanding of lambda's
"genetic switch." The study of lambda reveals the basic reactions
that underlie transcriptional regulation in all organisms and shows
how those reactions can be combined to produce a complex regulatory
circuit."--BOOK JACKET.
Notes:
Includes bibliographical references and index.
Ch. 1. The master elements of control -- Ch. 2. Protein-DNA
interactions and gene control -- Ch. 3. Control circuits - setting
the switch -- Ch. 4. How do we know - the key experiments -- Ch. 5.
2004: new developments.
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