Featuring more than 4100 references, Drug-Induced Liver Disease will
be an invaluable reference for gastroenterologists, hepatologists,
family physicians, internists, pathologists, pharmacists,
pharmacologists, and clinical toxicologists, and graduate and medical
school students in these disciplines.
Notes:
Preface; Contents; Contributors; Drug-Induced Liver Disorders:
Introduction and Overview; The Role of Cytochrome P450s in
Drug-Induced Liver Disease; Oxidative Stress, Antioxidant Defense,
and Liver Injury; Hepatotoxicity Due to Mitochondrial Injury;
Mechanisms of Cell Death and Relevance to Drug Hepatotoxicity; The
Role of Membrane Transport in Drug-Induced Hepatotoxicity and
Cholestasis; Immunological Mechanisms in Liver Injury; Mechanistic
Role of Acyl Glucuronides; Nonparenchymal Cells, In.ammatory
Macrophages, and Hepatotoxicity.
Roles of Cytokines and Growth Factors in Liver Regeneration, Repair,
and Fibrosis after Liver InjuryClinicopathological Patterns of
Drug-Induced Liver Disease; Histopathology of Drug-Induced Liver
Disease; Mechanisms of Acetaminophen - Induced Liver Disease;
Acetaminophen: Pathology and Clinical Presentation of Hepatotoxicity;
Mechanisms Underlying the Hepatotoxicity of Nonsteroidal
Anti-In.ammatory Drugs; Nonsteroidal Anti-In.ammatory Drugs:
Pathology and Clinical Prese.
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