"Cardiovascular Toxicology examines how chemicals and drugs may
adversely affect the normal functioning of the heart and circulatory
system. This newly revised edition begins with recent advances on the
molecular aspects of toxicity, including information on genomics, and
takes the reader up-to-date with the latest methods for investigating
acute and chronic toxicity and the techniques used to assess
cardiovascular function. It then goes on to examine cell injury with
emphasis placed on the roles of apoptosis, oncosis and necrosis in
explaining how chemicals adversely affect the cardiovascular system.
An examination of the pathological mechanism of ischemic heart
disease is also included." "The next section provides comprehensive
coverage of the toxicity of a wide range of chemicals such as
antibiotics, endotoxins, catecholamine, CNS acting drugs, ion channel
inhibitors, anti-cancer compounds and steroids. A chapter discusses
the role that passive smoking may have on the functioning of the
heart and its relation to heart disease. Others focus on other
well-known environmental pollutants and their fate in the
cardiovascular system." "For many years, too little attention has
been paid to the effects of chemicals on the vasculature. This book
addresses the situation by including a section devoted to the
cellular and molecular effects of chemicals on blood vessels,
biological mechanisms of injury to the vasculature and the responses
of blood vessels to toxins." "With contributions from leading experts
in this field, Cardiovascular Toxicology is the essential resource
for students of toxicology, clinicians, public health officials,
industrial and experimental toxicologists, and other professionals in
these fields."--BOOK JACKET.
Notes:
Includes bibliographical references and index.
Book Details:
Language: eng
Physical Description: xvi, 594 p. : ill. ; 24 cm.
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