Biotransformations in Organic Chemistry: A Textbook Kurt Faber, K. Faber,
Publisher: Springer-Verlag
ISBN: 3540200975
Edition: Paperback; 2004-03-05
Summary:
The use of biocatalysts, employed either as isolated enzymes or whole
microbial cells, offers a remarkable arsenal of highly selective
transformations for state-of-the-art synthetic organic chemistry.
Over the last two decades, this methodology has become an
indispensable tool for asymmetric synthesis, not only at the academic
level, but also on an industrial scale. This well-established
textbook on biocatalysis provides a basis for undergraduate and
graduate courses in modern organic chemistry, as well as a condensed
introduction into this field. After a basic introduction into the use
of biocatalysts ? principles of stereoselective transformations,
kinetics and enzyme properties ? the different types of reactions are
explained according to the 'reaction principle', such as hydrolysis,
reduction, oxidation, C-C bond formation, etc. Special techniques,
such as the use of enzymes in organic solvents, immobilization
techniques and the use of modified enzymes, are treated in a separate
section. A final chapter deals with the basic rules for the safe and
practical handling of biocatalysts. In this revised and corrected 5th
edition, emphasis has been given to an improved didactic style in
order to facilitate a deeper understanding of the underlying
principles. New developments, such as dynamic resolution,
stereo-inversion and enantio-convergent processes are included.
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