The therapeutic use of angiotensin converting enzyme (ACE) inhibitors
is subject of this monograph, written by international experts in the
field. Elegantly introduced by a historical perspective by Sir John
Vane, Nobel Laureate, the book covers major topics ranging from the
molecular basis of the ACE inhibitors to their application in several
diseases of paramount importance such as hypertension, renal failure,
diabetes and heart failure. Additional contributions address the
multitude of peripheral factors which may modulate the efficacy
and/or activity of the ACE inhibitors. >From a description of the
genetic basis of ACE to epidemiological considerations on these
potent molecules, this treatise should be of great benefit to
clinical and non-clinical scientists, residents, the pharmacological
industry and the decision-makers in health policy, providing the
reader with a comprehensive review of the field of ACE inhibitors.
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