000 01973cam 2200373 a 4500
001 1875981
005 20050607123701.0
008 040113s2004 nyua b 001 0 eng
010 $a 2004000803
020 $a0879697164 (pbk. : alk. paper)
020 $a0879697172 (cloth)
035 $a(CaOOAMICUS)000025281075
035 $a1875981
040 $aDNLM/DLC$beng$cDLC$dDLC$dOrLoB-B
042 $apcc
050 00 $aQR342$b.P83 2004
060 10 $aQW 161.5.C6$bP975g 2004
082 00 $a579.2/6$222
100 1 $aPtashne, Mark.
245 12 $aA genetic switch :$bphage lambda revisited
/$cMark Ptashne.
250 $a3rd ed.
260 $aCold Spring Harbor, N.Y. :$bCold Spring Harbor
Laboratory Press,$cc2004.
300 $axiv, 154 p. :$bill. (some col.) ;$c23 cm.
504 $aIncludes bibliographical references and index.
505 0 $aCh. 1. The master elements of control -- Ch. 2.
Protein-DNA interactions and gene control -- Ch. 3. Control
circuits - setting the switch -- Ch. 4. How do we know - the
key experiments -- Ch. 5. 2004 : new developments.
520 1 $a"The first edition of A Genetic Switch has become
a classic exposition of gene regulation, explaining in
simple molecular terms how proteins bind DNA and turn genes
on and off as the virus lambda grows in bacteria. To that
original text, reprinted here with small modifications, the
author has added a chapter describing recent advances that
extend and deepen our understanding of lambda's "genetic
switch." The study of lambda reveals the basic reactions
that underlie transcriptional regulation in all organisms
and shows how those reactions can be combined to produce a
complex regulatory circuit."--BOOK JACKET.
650 0 $aBacteriophage lambda.
650 0 $aGenetic regulation.
650 0 $aViral genetics.
650 12 $aBacteriophage lambda$xgenetics.
650 22 $aGene Expression Regulation.
650 22 $aGenes, Viral.
650 22 $aLysogeny.
650 22 $aRepressor Proteins.